LEE Gregory and Jordan Archer are unlikely to be involved against Shrewsbury Town on Tuesday night.
The pair could return for the trip to Gillingham next Saturday.
Lions boss Neil Harris has no other injury worries and has a difficult choice to make who to play in the centre of defence.
Shaun Hutchinson made an eye-catching return from injury in the 3-1 win over Scunthorpe after his latest injury lay-off, partnering Byron Webster, with Jake Cooper dropping to the bench.
"I think every Millwall fan that has seen Hutch play has been impressed by him," Harris said. "I knew what a good player he was when I brought him in in the summer. I was extremely lucky to get him.
"He's had a tough start to his Millwall career but when he's played he has been excellent. He's had a lot of time on the sideline watching Coops and Webbie play very well.
"Going into Tuesday night we have three excellent options at centre-half and with Coops rested it's a tough decision for me."
Shrewsbury are without suspended midfielder Ryan Yates. Abu Ogogo is a long-term absentee.
Paul Hurst's side are fourth last, two points behind Gillingham with a game in hand. They haven't won since February 28 when they defeated Charlton Athletic 4-3 at Greenhous Meadow.
They defeated Millwall 1-0 at The Den in December (above) and Hurst is hoping an early goal for his side could turn up the pressure on the visitors on Tuesday night.
"The overall picture is extremely tight and obviously at the weekend we dropped into the relegation zone," Hurst told the club's official website.
"Games are running out, but we've got a chance. We've still got six games starting with the Millwall game and as I said in an interview on Saturday I've certainly not given up and will keep fighting.
"I think no matter what, you expect it to be tough.
"What I would say about Millwall is that they very much have something to play for. I think if they are looking to get in the play-offs themselves they will be looking at this game thinking that they will need three points, so we've got to try and upset that first and foremost.
"Who knows how the game's going to pan out tomorrow, but if for instance we get in front are they going to start panicking or are they going to play with less pressure?
"I don't think you can ever be fully sure, but because we've both still got something to play for there might be an element of dealing with pressure for both teams at some points."
Millwall record against Shrewsbury Town:
Won 17 Drawn 9 Lost 12
Probable Millwall team:
4-4-2: King; Romeo, Webster, Hutchinson, Craig; Wallace, Thompson, Williams, Ferguson; O'Brien, Morison.
Shrewsbury 14/5 Draw 5/2 Millwall 19/20
Image: Millwall FC