|Venue: The Den
|Pogrebnyak 40, Pearce 72, Williams 76|
MILLWALL were well-beaten by play-off chasing Reading as boss Ian Holloway suffered his first home defeat in charge.
Stephen Bywater's error was punished by Pavel Pogrebnyak five minutes before half time to give the Royals the lead, and the Lions never recovered.
Defender Alex Pearce hammered in the second goal before, moments later, the ball broke kindly for Daniel Williams to make it 3-0.
Holloway made five changes following the midweek draw with Sheffield Wednesday.
Josh Wright, Liam Feeney, Mark Beevers, Shaun Williams and DJ Campbell all came into the side at the expense of Nicky Bailey, Lee Martin, Shane Lowry, Liam Trotter and Andy Keogh.
Visiting goalkeeper Alex McCarthy was called into action in the third minute to keep out Campbell's snap shot as Millwall made a bright start.
Jobi McAnuff's cross-shot rolled narrowly wide of the far post before Steve Morison's volley from a corner flew over the bar at the other end.
In the 17th minute, Jordan Obita's curling free kick was tipped behind by Bywater as the Royals began to tighten their grip on the game.
Top-scorer Adam Le Fondre should have done better when Garath McLeary stabbed the ball through to him inside the area, but the striker sliced wide.
Martyn Woolford tried his luck from distance after a mazy run down the centre of the field, but the ball bobbled at the crucial moment and he scooped his shot over.
Reading broke the deadlock out of nothing when Bywater inexcusably fumbled a high cross under pressure from Le Fondre, and Pogrebnyak steadied himself before scoring.
Le Fondre should have made it 2-0 in first-half injury time but he got his near-post header all wrong when it looked easier to score.
Six minutes after the restart, Feeney broke clear down the right channel but, under pressure, shot straight at McCarthy from a tight angle.
Holloway brought on Jermaine Easter and Lee Martin in a bid to inject some attacking flair into his side before replacing Beevers with John Marquis as he chased an equaliser.
But that gamble did not pay off and barely 60 seconds after Beevers was withdrawn, Pearce scored from close range after Pogrebnyak's header was parried by Bywater.
Williams' initial effort was blocked but the ball rebounded straight back to him and the midfielder stabbed in to make it 3-0.
Reading stopper McCarthy made his first meaningful save of the second period when he tipped Marquis' looping header over the bar in the 83rd minute.
Only Charlton's collapse at Wigan, where they were leading 1-0 but lost 2-1, prevented the Lions from slipping into the relegation zone.